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IGF-1 DES is a truncated form of IGF-1 with the tri-peptide structure Glycine-Proline-Glutamine cleaved from the N-terminus. It has been isolated from and detected in numerous in vivo sources, including the human brain, bovine colostrum, and porcine uterus. In vitro studies demonstrate that at equal doses DES(1-3)IGF is ten times more potent than IGF-1 at stimulating hypertrophy and proliferation in cultured cells.
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